It has been investigated the influence of cytotoxic components of the blood serum of patients with critical conditions (acute varicose thrombosis end deep vein thrombosis, myasthenia gravis, biliary cirrhosis, pancreatonecrosis, burns.) on the cells of microalgae Dunaliella viridis. The responses of bioindicator cells indicate about the presence mechanisms of cytotoxic actions affecting the metabolic activity, the functioning of the membrane complex, the ion channels of cells. Qualitative and quantitative differences between the reactions of microalgae, as well as the concentration dependence of cytotoxic factors indicate that the number and nature of these factors is different at different critical conditions.

Keywords: cytotoxicity, bioindication, sensitive, express method

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